Terry Benedict locates all eleven members of Danny Ocean's crew, demanding they return the $160 million they stole from his casinos plus $38 million interest. Short by half, the group schemes to stage another heist in Amsterdam to avoid problems with U.S. authorities. They are tipped off by an informant named Matsui about the location of the first stock certificate ever. After a complex series of schemes, they find the document has already been stolen by the "Night Fox", another master thief. Europol Detective Isabel Lahiri is called in to investigate the theft and realizes that she gave Rusty the idea of how to solve a complication of the heist with a description of a similar burglary earlier during their relationship. Surprising the group at their accommodation, she warns them they cannot beat the Night Fox or his mentor, the mysterious master-thief known as "LeMarc", both of whom excel in practicing the "long-con". She has been hunting both for years.
Danny and his gang discover the Night Fox is François Toulour, a wealthy French baron who has a villa on Lake Como. Toulour invites Danny to his villa and reveals that he had exposed their identities to Benedict and hired Matsui to inform the crew about the certificate in order to arrange the meeting with Danny. Toulour is upset that LeMarc suggested Danny may be a better thief than him and challenges Danny to steal the Fabergé Imperial Coronation Egg. If Danny and his crew win, Toulour will pay off the debt to Benedict.
Danny and his gang begin to plan an elaborate heist to swap the egg for a holographic recreation, but the engineer hired by the group accidentally tips off Lahiri to their presence, and she captures all of the crew except Linus, Tarr, Turk, and Saul. Linus comes up with a second plan involving Danny's wife, Tess, posing as a pregnant Julia Roberts in order to get close to the Egg and swap it. They are foiled by Lahiri and a coincidentally present Bruce Willis, and the rest of the group are captured. Lahiri is told that they are to be extradited to the U.S. Linus is chosen first to be interrogated by the FBI agent assigned to collect them. It turns out that she is his mother, who organizes the release of the whole gang. She points out to Lahiri that she will face only retribution for forging a signature on a Europol form to obtain the necessary arrest warrants for Ocean's gang.
Some time later, Danny and Tess return to Toulour's estate where he reveals his glee at their failure. Toulour explains he stole the egg at night using his agility and dancing skills to evade its heavy security. Toulour's celebration is short-lived when Danny reveals that his group stole the real egg while it was in transit to the museum, and Toulour realizes they were tipped off by LeMarc. A flashback reveals that Danny and Rusty had met LeMarc earlier when he revealed his confidence trick intended to humiliate Toulour, and at the same time, to restore to himself the Fabergé egg that he had stolen years ago and had returned following his wife's wishes. Toulour is forced to admit Danny won the bet and gives him the money for the debt. They pay back Benedict and promise not to perform any more heists in his casinos as Toulour is in the background spying on Benedict. Rusty takes Lahiri to a safe house that he claims has been lent to him by LeMarc. She is reunited with her father, who is revealed to be the man she has been pursuing for years: LeMarc.